The Mystery Inc. gang meet with their friend, Eric Staufer, a computer science major at the university, who created a laser that has the ability to send people into cyberspace. A video game featuring Scooby and the gang was designed to test the laser, but during the test, a Phantom Virus has escaped from cyberspace, and begins wreaking havoc in the university. Can Mystery Inc. stop the Phantom Virus, and find out who is responsible for releasing it? In Scooby-Doo and the Cyber Chase for Gameboy Advance, you must discover the identity of the suspect responsible for unleashing the Phantom Virus. This is done by navigating seven levels; the main lab level, which contains CDs, grant access to six additional levels, which may only be reached via the computer in cyberspace, and the laser in the robotics lab section of the main level sends a character there. Each member of the Mystery Inc. gang is available, but only one character may play at a time. Only two CDs are available at the start. Two additional CDs are gained upon completion of a computer level, which appear in the main lab level in the Computer Lab room, and when picked up unlocks more computer levels in the game to complete. You cannot enter the computer levels unless you pick up the CDs from the main lab level.
| Boxed A | Factory Sealed Product |
| Boxed B | Product Boxed & Complete with Manual |
| Boxed C | Product Boxed without Manual |
| D | Loose Item |
